2. Natural Products
  3. Alkaloids
  4. Indole Alkaloids

Indole Alkaloids

Indole Alkaloids (460):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15141
    Staurosporine 62996-74-1 99.77%
    Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer.
    Staurosporine
  • HY-A0190
    Caerulein 17650-98-5 99.96%
    Caerulein is a decapeptide and a potent cholecystokinin receptor agonist. Caerulein is a safe and effective cholecystokinetic agent with a direct spasmogenic effect on the gallbladder muscle and bile ducts.
    Caerulein
  • HY-B1473A
    Serotonin 50-67-9 99.86%
    Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
    Serotonin
  • HY-B1473
    Serotonin hydrochloride 153-98-0 99.97%
    Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist, with blood-brain barrier permeability. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
    Serotonin hydrochloride
  • HY-W028393
    Indole-3-pyruvic acid 392-12-1 99.55%
    Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety.
    Indole-3-pyruvic acid
  • HY-N4012
    Indole-3-glyoxylamide 5548-10-7 98.0%
    Indole-3-glyoxylamide (Compound 4) is a type of indole alkaloid. Indole-3-glyoxylamide shows no significant cytotoxic activity against Hela, Ishikawa, and MGC-803 cells.
    Indole-3-glyoxylamide
  • HY-N17166
    Cristatumin E 1459722-08-7
    Cristatumin E (Eurocristatine) is a natural alkaloid.
    Cristatumin E
  • HY-N19716
    Austamide 34427-31-1
    Austamide is an indole alkaloid found in cultures of Aspergillus ustus. Austamide undergoes biosynthesis via the classical mevalonate pathway with nonface-selective reverse prenylation of its indole ring.
    Austamide
  • HY-N0737A
    Harmine 442-51-3 99.97%
    Harmine is a natural dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor with anticancer and anti-inflammatory activities. Harmine has a high affinity of 5-HT2A serotonin receptor, with an Ki of 397 nM.
    Harmine
  • HY-N0127
    Yohimbine Hydrochloride 65-19-0 99.92%
    Yohimbine hydrochloride is an alpha-2 renal adenomatase receptor inhibitor, blocking pre- and post-contact alpha-2 renal adenomatase receptors, causing the release of renal adenoma and multiple sclerosis.
    Yohimbine Hydrochloride
  • HY-N0480
    Reserpine 50-55-5 99.92%
    Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).
    Reserpine
  • HY-W007376
    Indole-3-carboxaldehyde 487-89-8 99.96%
    Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract.
    Indole-3-carboxaldehyde
  • HY-N0170
    Indole-3-carbinol 700-06-1 99.16%
    Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an Aryl hydrocarbon receptor (AhR) agonist, and an inhibitor of WWP1 (WW domain-containing ubiquitin E3 ligase 1).
    Indole-3-carbinol
  • HY-N7131
    Coumarin 6 38215-36-0 99.59%
    Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λexc=450 nm, λem=505 nm).
    Coumarin 6
  • HY-W001132
    Indole 120-72-9 99.99%
    Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule.
    Indole
  • HY-N0114
    Evodiamine 518-17-2 99.97%
    Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor.
    Evodiamine
  • HY-N6771
    Cyclopiazonic acid 18172-33-3 99.86%
    Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC50 value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B[1][4][5].
    Cyclopiazonic acid
  • HY-N0117
    Indirubin 479-41-4 98.76%
    Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia.
    Indirubin
  • HY-40161
    Indole-3-carboxylic acid 771-50-6 99.96%
    Indole-3-carboxylic acid is an orally active urinary indolic tryptophan metabolite. Indole-3-carboxylic acid is a mediator of priming against Plectosphaerella cucumerina. Indole-3-carboxylic acid enhances the anti-colorectal cancer potency of Doxorubicin (HY-15142A) by inducing cell senescence. Indole-3-carboxylic acid can be used in liver disease research.
    Indole-3-carboxylic acid
  • HY-N6732
    K-252a 99533-80-9 99.45%
    K-252a, a staurosporine analog, inhibits protein kinase, with IC50 values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively. K-252a is a potent inhibitor (IC50 of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene.
    K-252a